The appeal of ActivePerl and ActivePython is obvious when you're running business applications in an exclusively Windows environment. There are other distributions of Perl and Python available for Windows, but none with a vendor like ActiveState backing them up.
When you create a pure Python sandbox using virtualenv --no-site-packages the global site-packages directory is rightfully not included ... however, this poses a challenge in accessing non-trivial packages from within the virtualenv.
We're very excited about the work we're doing with Python these days here at ActiveState. It's been a great year for both Patriots & Python fans, so I though before I shut down my computer to turn my focus to football and turkey, I wanted to reflect on why I am so thankful for Python.